· Issue Nº 001
TilTaken.
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The big table.

Nine medications. Nine supplements. Duration, generic price, side effects, and how much proof exists for each.

Brand / genericClassLastsGeneric price*Common side effectsWorth knowing
Adderall IRmixed amphetamine saltsStimulant (amphetamine)4–6 h$20–40/moAppetite loss, insomnia, dry mouth, anxietyShort-acting; often dosed twice daily.
Adderall XRmixed amphetamine salts ERStimulant (amphetamine)8–12 h$25–60/moAppetite loss, insomnia, dry mouthExtended release; once-daily morning dose.
VyvanselisdexamfetamineStimulant (amphetamine)10–14 h$60–120/moAppetite loss, insomnia, irritabilityProdrug — smoother onset, lower abuse potential. Generic since 2023.
Ritalin IRmethylphenidateStimulant (methylphenidate)3–5 h$15–30/moAppetite loss, insomnia, stomach acheShortest-acting option; fast on, fast off.
Concertamethylphenidate ERStimulant (methylphenidate)10–12 h$30–70/moAppetite loss, insomnia, headacheOROS pump delivery — steady release across the day.
Focalin XRdexmethylphenidate ERStimulant (methylphenidate)8–12 h$30–70/moAppetite loss, anxiety, dry mouthRefined isomer of methylphenidate; some tolerate it better.
StratteraatomoxetineNon-stimulant24 h$25–60/moNausea, fatigue, decreased appetiteNot a controlled substance. Takes 2–6 weeks for full effect.
Qelbreeviloxazine ERNon-stimulant24 h$300+/mo (no generic)Sleepiness, nausea, decreased appetiteNewest non-stimulant; no generic yet, so pricey.
Intunivguanfacine ERNon-stimulant24 h$15–35/moDrowsiness, low blood pressure, dizzinessOften added to a stimulant; helps with emotional regulation.

*Typical US discounted-generic cash price ranges; varies by pharmacy and dose. Informational only — not medical advice. Talk to your prescriber. Sources: FDA prescribing information.

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